Principles of brain wiring
Using network science as a general framework to study the network architecture of nervous system connectivity, more and more studies have highlighted the human and animal brain to display features of an efficient communication network. In my talk I will discuss potential general principles of wiring ofconnectome organization, principles conserved across species, and which may play an important role in general nervous system functioning. I will highlight findings that show connectomes to display cost-effective wiring, pronounced community structure, short communication relays, and the existence ofrichly connected ‘hub regions’. I will discuss theories on how these themes of wiring may play a role in brain disorders, as well as establish a putative link between the micro- and macroscale organization of the human brain in health and disease.
- Comparative Connectomics (https://www.ncbi.nlm.nih.gov/pubmed/27026480)
- The economy of brain network organization (https://www.ncbi.nlm.nih.gov/pubmed/22498897)
- Linking macroscale graph analytical organization to microscale neuroarchitectonics in the macaque connectome (https://www.ncbi.nlm.nih.gov/pubmed/25186762)
- Meta-connectomics: human brain network and connectivity meta-analyses (https://www.ncbi.nlm.nih.gov/pubmed/26809184)