Principles of brain wiring

divendres, 2017, novembre 24 - 12:00
Department of psychiatry, University Medical Center Utrecht, The Netherlands

Abstract

 

Using network science as a general framework to study the network architecture of nervous system connectivity, more and more studies have highlighted the human and animal brain to display features of an efficient communication network. In my talk I will discuss potential general principles of wiring ofconnectome organization, principles conserved across species, and which may play an important role in general nervous system functioning. I will highlight findings that show connectomes to display cost-effective wiring, pronounced community structure, short communication relays, and the existence ofrichly connected ‘hub regions’. I will discuss theories on how these themes of wiring may play a role in brain disorders, as well as establish a putative link between the micro- and macroscale organization of the human brain in health and disease.

 

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