Auditory stimuli may be a good marker for early diagnosis of Alzheimer’s disease

Segons un treball publicat a Scientific Reports, per Manuela Ruzzoli, investigadora del Centre de Cognició i Cervell i primera autora de l'article, que explora la fiabilitat de l'estímul sonor com a possible marcador de demència.

The evidence suggests that Alzheimer’s disease is part of a continuum, characterized by long pre-clinical phases that precede the onset of the symptoms of the disease. In several cases, this continuum begins with mild cognitive impairment (MCI), in which daily activities are preserved despite the presence of certain cognitive impairment, mostly through aspects of memory.

The possibility of having a reliable and sensitive neurophysiological marker that could be used for early detection of Alzheimer’s disease would be an extremely valuable diagnostic tool in a highly prevalent disease. A study published in September in Scientific Reports, sought to find the reliability of auditory mismatch negativity (aMMN) as a marker capable of identifying the progression of mild cognitive impairment in Alzheimer’s disease. A study by Manuela Ruzzoli, first author of the paper and researcher at the Center for Brain and Cognition (CBC) of the Department of Information and Communication Technologies (DTIC) at UPF, in collaboration with Italian researchers at the University of Trento and the San Giovanni di Dio Centre in Brescia. (